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GTP diphosphokinase
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GTP diphosphokinase : ウィキペディア英語版
GTP diphosphokinase

In enzymology, a GTP diphosphokinase () is an enzyme that catalyzes the chemical reaction
:ATP + GTP \rightleftharpoons AMP + guanosine 3'-diphosphate 5'-triphosphate
Thus, the two substrates of this enzyme are ATP and GTP, whereas its two products are AMP and guanosine 3'-diphosphate 5'-triphosphate.
This enzyme belongs to the family of transferases, specifically those transferring two phosphorus-containing groups (diphosphotransferases). The systematic name of this enzyme class is ATP:GTP 3'-diphosphotransferase. Other names in common use include stringent factor, guanosine 3',5'-polyphosphate synthase, GTP pyrophosphokinase, ATP-GTP 3'-diphosphotransferase, guanosine 5',3'-polyphosphate synthetase, (p)ppGpp synthetase I, (p)ppGpp synthetase II, guanosine pentaphosphate synthetase, GPSI, and GPSII. This enzyme participates in purine metabolism.
==Structural studies==

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and .

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